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蛋白质芯片:英文本

蛋白质芯片:英文本

作者:(美)M.谢纳著

出版社:科学出版社

出版时间:2005-04-01

ISBN:9787030151834

定价:¥65.00

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内容简介
  人类基因组大规模测序工作已经完成,随着以功能基因组学和蛋白质组学为主要研究内容的后基因时代来临,蛋白质芯片作为检测蛋白质存在和运动变化的高效工具,将为本世纪的疾病诊断和治疗、新药开发、分子生物学、航空航天、司法鉴定、食品卫生及环境监测等领域带来一场革命。生物芯片技术是一种高通量检测技术,它包括基因芯片、蛋白质芯片及芯片实验三大领域。蛋白质芯片以蛋白质代替DNA作为检测目的物,此基因芯片更接近生命活动的物质层面,以直接测定蛋白质的相对水平及与其他分子在交互作用情况,以定量化的方式反映基因的活动情况,因而蛋白质芯片有着比基因芯片更加直接的应用前景。《蛋白质芯片(影印版)》对蛋白质芯片技术进行了全面细致地阐述,包括技术原理、生产方法、表面化学、检测策略以及抗原、抗体数据分析,同时全书图文并茂,提供了许多生物学应用实例及实验草案。《蛋白质芯片(影印版)》知识全面,内容丰富,集合了蛋白质芯片技术的基础知识和前沿研究,实用性广泛,可读性强。适用于从事生物芯片研究开发以及生物信息学、蛋白质组学、基因组学、分子生物学、生物化学、细胞生物学、生物技术等相关研究领域的教学科研人员或技术人员参考使用,也可做为研究生教材。
作者简介
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目录
Table of Contents
List of Contributors
Preface
Foreword
Chapter 1
Principles of Protein Microarrays
Mark Schena
Chapter 2
Novel Strategies in Protein Microarray Generation and Detection
Yee-Peng Rina Lue, Su-Yin Dawn Yeo, Lay-Pheng Tan, Mahesh Uttamchandani, Grace Yi-Jun Cben, and Shao Q. Yao
Chapter 3
Practical Guide to Protein Microarrays: Assay Systems, Methods, and Algorithms
Mikhail Soloviev and Jon Terrett
Chapter 4
Microarrays for the High-Throughput Analysis of Protein-Carbohydrate Interactions
William G. T. Willats
Chapter 5
Protein Microarrays: Principles and Limitations
Victor N. Morozov
Chapter 6
System-Oriented Proteomics Using Protein-Domain Microarrays
Alexsandra Espejo and Mark T. Bedford
Chapter 7
Colorimetric Microarray Assays for Rheumatoid Arthritis using a Recombinant Proteome Library
Stewart J. Lebrun
Chapter 8
Academic and Commercial Aspects of Protein Microarray Development
Seung-yong Seong
Chapter 9
Analyzing Proteins and Protein Modifications with ArrayTubeTM Antibody Microarrays
Stefan W6lfl, Annegret Dummer, Larissa Pusch, Marina efalz, Lin Wan, Joachim H. Clement, lnes Leube, and Ralf Ehricht
Chapter 10
Non-Contact Dispensing for Protein Microarrays
Thomas C. Tisone and John L. Tonkinson
Chapter 11
High Speed, High Efficiency Protein Printing by BioLPTM
Bradley R. Ringeisen, Jason A. Barron, and David B. Krizman
Chapter 12
Putting the "BID" in Biochips: Capture Agents for Protein Microarray Expression Profiling Platforms
David S. Wilson, Michael L. Phelan, and Steffen Nock
Chapter 13
Protein Biochips for the Profiling of Allergen-Specific Antibodies
Christian Harwanegg, Susanne Spitzauer, Rudolf Valenta, Manfred W. Mueller, and Reinhard Hiller
Chapter 14
Solid Supports for Protein Microarrays and Related Devices
Wlad Kusnezow, Timo Pulli, Olaf Witt, and J6rg D. Hoheisel
Chapter 15
Protein Microarrays for Biosensor Applications
Michael G. Weller
Chapter 16
Technological Aspects of Protein Microarrays and Nanoarrays
Fan-Gang Tseng, Shih-Chang Lin, Da-Jen Yao, Haimei Huang, and Ching-Chang Chieng
Chapter 17
Mega-Dense Nanoarrays: The Challenge of Novel Antibody Microarray Formats
Christer Wingren, Lars Montelius, and CarlA. K. Borrebaeck
Chapter 18
INFINITITM System: An Automated Multiplexing Protein Microarray Platform
Anupam Talapatra, Vijay Mahant, Ram Vairavan, Fareed Kureshy, and Gary Hardiman
Chapter 19
Protein Microarrays for Analysis of Antibody Responses in Animals and Humans
Paul J. Utz, Lawrence Steinman, and William H. Robinson
Chapter 20
G-Protein Coupled Receptor Microarrays: A Versatile Tool fo Drug Discovery
Ye Fang, Yulong Hong, Jinlin Peng, and Joydeep Lahiri
Chapter 21
Proteome-Scale Analysis of the Immune Response Against Pathogenic Microorganisms
Tito Bacarese-Hamilton, Julian Gray, and Andrea Crisanti
Chapter 22
Development of Protein Microarrays for Drug Discovery...
Jens O. Koopmann, Michael B. McAndrew, and Jonathan M. Blackburn
Chapter 23
Development and Applications of Functional Protein Microarrays
James Ball, Barry Schweitzer, Paul Predki, and Michael Snyder
Chapter 24
Enabling Tools for Protein Microarrays
Todd Martinsky
IndexFFFF
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