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威廉姆斯内分泌学（中文精要+英文影印版）
作者：[美] 什洛莫·梅尔梅德 等 编，王卫庆 主译
出版社：上海科学技术出版社
出版时间：2022-10-01
ISBN：9787547858486
定价：¥680.00
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内容简介
《威廉姆斯内分泌学》是国际著名的**级医学巨著，是欧美经典内分泌学教科书。该书于20世纪50年代首次出版，目前已经修订至第14版。第14版共9篇46章，所述内容包括激素和激素作用、下丘脑和垂体、甲状腺、肾上腺皮质和内分泌性高血压、生殖、内分泌和生命谱、矿物质代谢、糖代谢紊乱、肥胖和脂代谢、多重内分泌紊、内分泌相关肿瘤综合征等。
作者简介
[美]什洛莫·梅尔梅德（Shlomo Melmed）：MB ChB，MACP，美国加州大学洛杉矶分校医学院副院长，Cedars-Sinai医学中心执行副总裁兼医学院院长。[美]理查德·J.奥胡斯（Richard J.Auchus），MD，PhD，美国密歇根大学药理学和内科学系代谢、内分泌和糖尿病科教授，美国弗吉尼亚州安娜堡医疗保健系统内分泌科科长。[美]艾利森·B.戈德法因（Allison B.Goldfine），MD，诺华生物医学研究所心脏代谢疾病转化医学主任，美国布里格姆妇女医院内分泌学、糖尿病和高血压科副医师，美国哈佛大学医学院兼职讲师。[美]罗纳德·J.凯尼格（Ronald J.Koenig），MD，PhD，美国密歇根大学内科学系代谢、内分泌和糖尿病科教授。[美]克利福德·J.罗森（Clifford J.Rosen），MD，美国塔夫茨大学医学院教授。
目录
中文精要 K1
■ 激素和激素作用 K2
1. 内分泌学原理 K2
2. 激素作用的原理 K2
3. 内分泌遗传学 K2
4. 诊断内分泌疾病的实验室技术 K2
5. 内分泌疾病的全球负担 K3
6. 内分泌学临床实践指南导读 K3
■ 下丘脑和垂体 K3
7. 神经内分泌学 K3
8. 垂体生理学与诊断评估 K3
9. 垂体肿物和肿瘤 K4
10. 垂体后叶 K4
■ 甲状腺 K4
11. 甲状腺病理生理学和诊断性评估 K4
12. 甲状腺功能亢进性疾病 K4
13. 甲状腺功能减退症和桥本甲状腺炎 K5
14. 非毒性弥漫性甲状腺肿、结节性甲状腺疾病和甲状腺恶性
肿瘤 K5
■ 肾上腺皮质和内分泌高血压 K5
15. 肾上腺皮质 K5
16. 内分泌高血压 K5
■ 性发育和功能 K6
17. 女性生殖轴的生理学和病理学 K6
18. 激素避孕 K6
19. 睾丸疾病 K6
20. 男性和女性性功能障碍 K7
21. 变性内分泌学 K7
■ 内分泌学和全生命周期 K8
A. 母胎 K8
22. 妊娠期内分泌变化 K8
23. 胎儿发育内分泌学 K8
B. 儿童 K8
24. 性发育异常疾病 K8
25. 儿童正常生长和异常生长 K9
26. 青春期生理学与疾病 K9
C. 成人 K9
27. 激素与运动 K9
28. 内分泌与衰老 K9
■ 矿物质代谢 K10
29. 激素与矿物质代谢紊乱 K10
30. 骨质疏松症的基础和临床 K10
31. 佝偻病和骨软化症 K10
32. 肾结石 K10
■ 碳水化合物和脂肪代谢性疾病 K11
33. 胰岛素分泌生理学 K11
34. 2型糖尿病的病理生理学 K11
35. 2型糖尿病的治疗 K11
36. 1型糖尿病 K12
37. 糖尿病并发症 K12
38. 低血糖 K12
39. 能量储存的神经内分泌调控 K13
40. 肥胖 K13
41. 脂代谢紊乱 K13
■ 多内分泌腺疾病和肿瘤性疾病 K13
42. 多发性内分泌腺瘤病 K13
43. 免疫性内分泌综合征 K14
44. 人类免疫缺陷病毒/获得性免疫缺陷综合征内分泌学 K14
45. 神经内分泌肿瘤和相关疾病 K14
46. 恶性肿瘤患者生殖障碍的管理 K14
_x000c_
XXII
威廉姆斯内分泌学
Contents
Section I: Hormones and Hormone Action
▲
1 Principles of Endocrinology
Shlomo Melmed, Richard J. Auchus, Allison B. Goldfine, Ronald J. Koenig,
Clifford J. Rosen, P. Reed Larsen, Kenneth S. Polonsky, and Henry M.
Kronenberg 2
2 Principles of Hormone Action
Evan D. Rosen and Christin Carter-Su 13
3 Genetics of Endocrinology
Robert L. Thomas, Joel N. Hirschhorn, and Amit R. Majithia 42
4 Laboratory Techniques for Recognition of Endocrine Disorders
Patrick M. Sluss and Frances J. Hayes 62
5 The Global Burden of Endocrine Diseases
Maria Inês Schmidt, Laercio J. Franco, Ewerton Cousin, and Bruce B.
Duncan 91
6 Navigating Through Clinical Practice Guidelines in
Endocrinology
Naykky Singh Ospina, Spyridoula Maraka, Rene Rodriguez-Gutierrez, Juan
P. Brito, and Victor Montori 103
Section II: Hypothalamus and Pituitary
7 Neuroendocrinology
Ronald M. Lechan 114
8 Pituitary Physiology and Diagnostic Evaluation
Ursula Kaiser and Ken Ho 184
9 Pituitary Masses and Tumors
Shlomo Melmed 236
10 Posterior Pituitary
Christopher J. Thompson and Joseph G. Verbalis 303
Section III: Thyroid
11 Thyroid Pathophysiology and Diagnostic Evaluation
Domenico Salvatore, Ronald Cohen, Peter A. Kopp, and P. Reed Larsen 332
12 Hyperthyroid Disorders
Anthony Hollenberg and Wilmar M. Wiersinga 364
13 Hypothyroidism and Thyroiditis
Gregory A. Brent and Anthony P. Weetman 404
14 Nontoxic Diffuse Goiter, Nodular Thyroid Disorders, and Thyroid
Malignancies
Sebastiano Filetti, R. Michael Tuttle, Sophie Leboulleux, and Erik K.
Alexander 433
Section IV: Adrenal Cortex and Endocrine Hypertension
15 The Adrenal Cortex
John D.C. Newell-Price and Richard J. Auchus 480
16 Endocrine Hypertension
William F. Young, Jr. 542
Section V: Sexual Development and Function
17 Physiology and Pathology of the Female Reproductive Axis
Serdar E. Bulun 574
18 Hormonal Contraception
Rebecca H. Allen, Andrew M. Kaunitz, Martha Hickey, and Annabelle
Brennan 642
19 Testicular Disorders
Alvin M. Matsumoto and Bradley D. Anawalt 668
20 Sexual Dysfunction in Men and Women
Shalender Bhasin and Rosemary Basson 756
21 Transgender Endocrinology
Stephen M. Rosenthal and Vin Tangpricha 796
Section VI: Endocrinology and the Life Span
Section VI A: Maternal-Fetal
22 Endocrine Changes in Pregnancy
Joshua F. Nitsche, Glenn D. Braunstein, and Sarah L. Berga 808
23 Endocrinology of Fetal Development
Harshini Katugampola, Evelien F. Gevers, and Mehul T. Dattani 825
Section VI B: Childhood
24 Disorders of Sex Development
Yee-Ming Chan, Sabine E. Hannema, John C. Achermann, and Ieuan A. Hughes 867
25 Normal and Aberrant Growth in Children
David W. Cooke, Sara A. DiVall, and Sally Radovick 937
26 Physiology and Disorders of Puberty
Dennis M. Styne 1023
Section VI C: Adult
27 Hormones and Athletic Performance
Fabio Lanfranco, Ezio Ghigo, and Christian J. Strasburger 1165
28 Endocrinology and Aging
Annewieke W. van den Beld and Steven W.J. Lamberts 1179
Section VII: Mineral Metabolism
29 Hormones and Disorders of Mineral Metabolism
F. Richard Bringhurst, Marie B. Demay, and Henry M. Kronenberg 1196
30 Osteoporosis: Basic and Clinical Aspects
Francisco J. A. de Paula, Dennis M. Black, and Clifford J. Rosen 1256
31 Rickets and Osteomalacia
Arti Bhan, Ajay D. Rao, Sanjay K. Bhadada, and Sudhaker D. Rao 1298
32 Kidney Stones
David A. Bushinsky 1318
Section VIII: Disorders of Carbohydrate and Fat Metabolism
33 Physiology of Insulin Secretion
Ele Ferrannini and Andrea Mari 1338
34 Pathophysiology of Type 2 Diabetes Mellitus
C. Ronald Kahn, Heather A. Ferris, and Brian T. O’Neill 1349
35 Therapeutics of Type 2 Diabetes Mellitus
Matthew C. Riddle and Andrew J. Ahmann 1371
36 Type 1 Diabetes Mellitus
Mark A. Atkinson, Dayna E. McGill, Eyal Dassau, and Lori Laffel 1403
37 Complications of Diabetes Mellitus
Michael Brownlee, Lloyd P. Aiello, Jennifer K. Sun, Mark E. Cooper, Eva L.
Feldman, Jorge Plutzky, and Andrew J. M. Boulton 1438
38 Hypoglycemia
Philip E. Cryer and Ana María Arbeláez 1525
39 Neuroendocrine Control of Energy Stores
Martin G. Myers, Jr., and David P. Olson 1552
40 Obesity
Eleftheria Maratos-Flier 1567
41 Disorders of Lipid Metabolism
Clay F. Semenkovich and Ira J. Goldberg 1581
Section IX: Polyendocrine and Neoplastic Disorders
42 Multiple Endocrine Neoplasia
Paul J. Newey and Rajesh V. Thakker 1622
43 The Immunoendocrinopathy Syndromes
Jennifer M. Barker, Peter A. Gottlieb, and Mark S. Anderson 1658
44 Endocrinology of HIV/AIDS
Todd T. Brown and Steven K. Grinspoon 1672
45 Neuroendocrine Tumors and Related Disorders
Kjell .berg 1691
46 Managing Reproductive Disorders in Cancer
Mahmoud Salama, Victoria Sandler, and Teresa K. Woodruff 1710
■ 激素和激素作用 K2
1. 内分泌学原理 K2
2. 激素作用的原理 K2
3. 内分泌遗传学 K2
4. 诊断内分泌疾病的实验室技术 K2
5. 内分泌疾病的全球负担 K3
6. 内分泌学临床实践指南导读 K3
■ 下丘脑和垂体 K3
7. 神经内分泌学 K3
8. 垂体生理学与诊断评估 K3
9. 垂体肿物和肿瘤 K4
10. 垂体后叶 K4
■ 甲状腺 K4
11. 甲状腺病理生理学和诊断性评估 K4
12. 甲状腺功能亢进性疾病 K4
13. 甲状腺功能减退症和桥本甲状腺炎 K5
14. 非毒性弥漫性甲状腺肿、结节性甲状腺疾病和甲状腺恶性
肿瘤 K5
■ 肾上腺皮质和内分泌高血压 K5
15. 肾上腺皮质 K5
16. 内分泌高血压 K5
■ 性发育和功能 K6
17. 女性生殖轴的生理学和病理学 K6
18. 激素避孕 K6
19. 睾丸疾病 K6
20. 男性和女性性功能障碍 K7
21. 变性内分泌学 K7
■ 内分泌学和全生命周期 K8
A. 母胎 K8
22. 妊娠期内分泌变化 K8
23. 胎儿发育内分泌学 K8
B. 儿童 K8
24. 性发育异常疾病 K8
25. 儿童正常生长和异常生长 K9
26. 青春期生理学与疾病 K9
C. 成人 K9
27. 激素与运动 K9
28. 内分泌与衰老 K9
■ 矿物质代谢 K10
29. 激素与矿物质代谢紊乱 K10
30. 骨质疏松症的基础和临床 K10
31. 佝偻病和骨软化症 K10
32. 肾结石 K10
■ 碳水化合物和脂肪代谢性疾病 K11
33. 胰岛素分泌生理学 K11
34. 2型糖尿病的病理生理学 K11
35. 2型糖尿病的治疗 K11
36. 1型糖尿病 K12
37. 糖尿病并发症 K12
38. 低血糖 K12
39. 能量储存的神经内分泌调控 K13
40. 肥胖 K13
41. 脂代谢紊乱 K13
■ 多内分泌腺疾病和肿瘤性疾病 K13
42. 多发性内分泌腺瘤病 K13
43. 免疫性内分泌综合征 K14
44. 人类免疫缺陷病毒/获得性免疫缺陷综合征内分泌学 K14
45. 神经内分泌肿瘤和相关疾病 K14
46. 恶性肿瘤患者生殖障碍的管理 K14
_x000c_
XXII
威廉姆斯内分泌学
Contents
Section I: Hormones and Hormone Action
▲
1 Principles of Endocrinology
Shlomo Melmed, Richard J. Auchus, Allison B. Goldfine, Ronald J. Koenig,
Clifford J. Rosen, P. Reed Larsen, Kenneth S. Polonsky, and Henry M.
Kronenberg 2
2 Principles of Hormone Action
Evan D. Rosen and Christin Carter-Su 13
3 Genetics of Endocrinology
Robert L. Thomas, Joel N. Hirschhorn, and Amit R. Majithia 42
4 Laboratory Techniques for Recognition of Endocrine Disorders
Patrick M. Sluss and Frances J. Hayes 62
5 The Global Burden of Endocrine Diseases
Maria Inês Schmidt, Laercio J. Franco, Ewerton Cousin, and Bruce B.
Duncan 91
6 Navigating Through Clinical Practice Guidelines in
Endocrinology
Naykky Singh Ospina, Spyridoula Maraka, Rene Rodriguez-Gutierrez, Juan
P. Brito, and Victor Montori 103
Section II: Hypothalamus and Pituitary
7 Neuroendocrinology
Ronald M. Lechan 114
8 Pituitary Physiology and Diagnostic Evaluation
Ursula Kaiser and Ken Ho 184
9 Pituitary Masses and Tumors
Shlomo Melmed 236
10 Posterior Pituitary
Christopher J. Thompson and Joseph G. Verbalis 303
Section III: Thyroid
11 Thyroid Pathophysiology and Diagnostic Evaluation
Domenico Salvatore, Ronald Cohen, Peter A. Kopp, and P. Reed Larsen 332
12 Hyperthyroid Disorders
Anthony Hollenberg and Wilmar M. Wiersinga 364
13 Hypothyroidism and Thyroiditis
Gregory A. Brent and Anthony P. Weetman 404
14 Nontoxic Diffuse Goiter, Nodular Thyroid Disorders, and Thyroid
Malignancies
Sebastiano Filetti, R. Michael Tuttle, Sophie Leboulleux, and Erik K.
Alexander 433
Section IV: Adrenal Cortex and Endocrine Hypertension
15 The Adrenal Cortex
John D.C. Newell-Price and Richard J. Auchus 480
16 Endocrine Hypertension
William F. Young, Jr. 542
Section V: Sexual Development and Function
17 Physiology and Pathology of the Female Reproductive Axis
Serdar E. Bulun 574
18 Hormonal Contraception
Rebecca H. Allen, Andrew M. Kaunitz, Martha Hickey, and Annabelle
Brennan 642
19 Testicular Disorders
Alvin M. Matsumoto and Bradley D. Anawalt 668
20 Sexual Dysfunction in Men and Women
Shalender Bhasin and Rosemary Basson 756
21 Transgender Endocrinology
Stephen M. Rosenthal and Vin Tangpricha 796
Section VI: Endocrinology and the Life Span
Section VI A: Maternal-Fetal
22 Endocrine Changes in Pregnancy
Joshua F. Nitsche, Glenn D. Braunstein, and Sarah L. Berga 808
23 Endocrinology of Fetal Development
Harshini Katugampola, Evelien F. Gevers, and Mehul T. Dattani 825
Section VI B: Childhood
24 Disorders of Sex Development
Yee-Ming Chan, Sabine E. Hannema, John C. Achermann, and Ieuan A. Hughes 867
25 Normal and Aberrant Growth in Children
David W. Cooke, Sara A. DiVall, and Sally Radovick 937
26 Physiology and Disorders of Puberty
Dennis M. Styne 1023
Section VI C: Adult
27 Hormones and Athletic Performance
Fabio Lanfranco, Ezio Ghigo, and Christian J. Strasburger 1165
28 Endocrinology and Aging
Annewieke W. van den Beld and Steven W.J. Lamberts 1179
Section VII: Mineral Metabolism
29 Hormones and Disorders of Mineral Metabolism
F. Richard Bringhurst, Marie B. Demay, and Henry M. Kronenberg 1196
30 Osteoporosis: Basic and Clinical Aspects
Francisco J. A. de Paula, Dennis M. Black, and Clifford J. Rosen 1256
31 Rickets and Osteomalacia
Arti Bhan, Ajay D. Rao, Sanjay K. Bhadada, and Sudhaker D. Rao 1298
32 Kidney Stones
David A. Bushinsky 1318
Section VIII: Disorders of Carbohydrate and Fat Metabolism
33 Physiology of Insulin Secretion
Ele Ferrannini and Andrea Mari 1338
34 Pathophysiology of Type 2 Diabetes Mellitus
C. Ronald Kahn, Heather A. Ferris, and Brian T. O’Neill 1349
35 Therapeutics of Type 2 Diabetes Mellitus
Matthew C. Riddle and Andrew J. Ahmann 1371
36 Type 1 Diabetes Mellitus
Mark A. Atkinson, Dayna E. McGill, Eyal Dassau, and Lori Laffel 1403
37 Complications of Diabetes Mellitus
Michael Brownlee, Lloyd P. Aiello, Jennifer K. Sun, Mark E. Cooper, Eva L.
Feldman, Jorge Plutzky, and Andrew J. M. Boulton 1438
38 Hypoglycemia
Philip E. Cryer and Ana María Arbeláez 1525
39 Neuroendocrine Control of Energy Stores
Martin G. Myers, Jr., and David P. Olson 1552
40 Obesity
Eleftheria Maratos-Flier 1567
41 Disorders of Lipid Metabolism
Clay F. Semenkovich and Ira J. Goldberg 1581
Section IX: Polyendocrine and Neoplastic Disorders
42 Multiple Endocrine Neoplasia
Paul J. Newey and Rajesh V. Thakker 1622
43 The Immunoendocrinopathy Syndromes
Jennifer M. Barker, Peter A. Gottlieb, and Mark S. Anderson 1658
44 Endocrinology of HIV/AIDS
Todd T. Brown and Steven K. Grinspoon 1672
45 Neuroendocrine Tumors and Related Disorders
Kjell .berg 1691
46 Managing Reproductive Disorders in Cancer
Mahmoud Salama, Victoria Sandler, and Teresa K. Woodruff 1710
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