书籍详情
Pharmaceutical Polymers（药用高分子）
作者：王者辉 著
出版社：化学工业出版社
出版时间：2018-10-01
ISBN：9787122324832
定价：¥88.00
购买这本书可以去
内容简介
《Pharmaceutical Polymers（药用高分子）》基于现代药剂学的发展，依据国内外新资料，结合作者多年来的教学科研实践编写而成，系统讲述了高分子在药物制剂中的应用。全书共分为十章，具体内容包括：药用高分子化学基础理论（章）；药用高分子的原理与结构（第二章）；天然来源与合成药用高分子（第三章）；天然来源高分子在药学领域的应用（第四章）；疏水性高分子聚合物的药用价值（第五章）；高分子聚合物在药物传递中的应用（第六章）；医药纳米技术（第七章）；药用高分子的热分析（第八章）；原子力显微镜在药用高分子中的应用（第九章）；药物高分子的流变学研究（第十章）。 《Pharmaceutical Polymers（药用高分子）》可供普通高等医药院校药学、药物制剂、制药工程、高分子材料与工程等相关专业学生及从事药物制剂生产、研究的人员参考使用。
作者简介
王者辉，泰山医学院，副教授， 自2004年以来，长期从事高分子材料专业的本、专科的教学，教授的课程主要有材料导论、专业英语、聚合物改性、涂料化学、光化学与光物理、波谱分析、聚合物加工流变学、高分子材料概论等。科研方向为医用高分子材料、高分子界面。
目录
Chapter 1 Fundamentals of Pharmaceutical Polymer Chemistry 1
1.1 The Concept of a Polymer 1
1.2 Addition Polymerization 4
1.3 Chain Branching; Graft and Block Copolymers 15
1.4 Polymer Structure and Properties 18
1.5 Technology of Polymerization 24
1.6 The Principal Monomers and Their Polymers 27
1.7 Physical Properties of Monomers 37
References 41
Chapter 2 Pharmaceutical Polymers: Principles and Structures 42
2.1 Introduction 42
2.2 Intra and Inter Polymer Molecular Interactions 45
2.3 Molecular Mass: Polydispersivity and Effects on Polymer Viscosity 47
2.4 Thermal Properties: Effect of Crystalline and Amorphous Phases 51
2.5 Mechanical Properties of Polymers 54
2.6 Pharmaceutical Polymers: Principles, Structures, and Applications of Pharmaceutical Delivery Systems 61
References 80
Chapter 3 Polymers as Drugs 81
3.1 Introduction 81
3.2 Polymers for Molecular Sequestration 83
3.3 Polyvalent Interactions and Anti-Infective Polymeric Drugs 95
3.4 Polymeric Drugs for the Treatment of Autoimmune Diseases 105
3.5 Polymeric Anti-Obesity Drugs 107
3.6 Polymer Therapy for Sickle Cell Disease 111
3.7 Conclusions and Outlook on Polymers as Drugs 112
References 113
Chapter 4 Pharmaceutical Applications of Natural Polymers 114
4.1 Introduction 114
4.2 Portals of Drug Administration in the Human Body 116
4.3 Transdermal Drug Delivery Devices 117
4.4 Topical Drug Delivery 124
4.5 Oral Drug Delivery System 131
4.6 Parenteral Drug Delivery Systems 132
4.7 Nasal Drug Delivery Systems 134
4.8 Hydrogel-Based Drug Delivery Systems 136
References 147
Chapter 5 Hydrophobic Polymers of Pharmaceutical Significance 149
5.1 Introduction 149
5.2 Examples of Hydrophobic Polymers and Their Drug Delivery Applications 150
5.3 Conclusions 167
References 168
Chapter 6 Polymers in Drug Delivery 169
6.1 Evolution of Drug Dosage Forms 169
6.2 Polymer Excipients 172
6.3 Polymers as Manufacture Aids and Sustained Release 174
References 200
Chapter 7 Pharmaceutical Nanotechnology: Overcoming Drug Delivery Challenges in Contemporary Medicine 202
7.1 Challenges in Delivery of Contemporary Therapeutics 202
7.2 Nanotechnology Solutions 207
7.3 Illustrative Examples of Nanotechnology Products 211
7.4 Multifunctional Nanotechnology 218
7.5 Regulatory Issues in Nano-pharmaceuticals 225
7.6 Conclusions and Future Outlook 235
References 235
Chapter 8 Thermal Analysis of Pharmaceutical Polymers 237
8.1 Introduction 237
8.2 Theoretical Background of Thermal Analysis 238
8.3 Physical and Chemical Phenomena Commonly Investigated Using Thermal Approaches 244
8.4 Applications of Thermal Analysis for the Characterisation of Pharmaceutical Raw Materials 248
8.5 Applications of Thermal Analysis for the Characterisation of Pharmaceutical Dosage Forms 250
8.6 Conclusion 255
References 255
Chapter 9 Applications of AFM in Pharmaceutical Polymers 256
9.1 Introduction 256
9.2 Use of AFM in Pharmaceutical Sciences 263
9.3 AFM Combined With Optical or Spectroscopic Techniques 271
9.4 Summary 271
References 273
Chapter 10 Rheology in Pharmaceutically Used Polymers 274
10.1 Introduction 274
10.2 Theoretical Background and Fundamental Concepts 275
10.3 Practical Issues of Rheological Measurements 289
10.4 Application of the Technique 292
10.5 Summary 297
References 297
1.1 The Concept of a Polymer 1
1.2 Addition Polymerization 4
1.3 Chain Branching; Graft and Block Copolymers 15
1.4 Polymer Structure and Properties 18
1.5 Technology of Polymerization 24
1.6 The Principal Monomers and Their Polymers 27
1.7 Physical Properties of Monomers 37
References 41
Chapter 2 Pharmaceutical Polymers: Principles and Structures 42
2.1 Introduction 42
2.2 Intra and Inter Polymer Molecular Interactions 45
2.3 Molecular Mass: Polydispersivity and Effects on Polymer Viscosity 47
2.4 Thermal Properties: Effect of Crystalline and Amorphous Phases 51
2.5 Mechanical Properties of Polymers 54
2.6 Pharmaceutical Polymers: Principles, Structures, and Applications of Pharmaceutical Delivery Systems 61
References 80
Chapter 3 Polymers as Drugs 81
3.1 Introduction 81
3.2 Polymers for Molecular Sequestration 83
3.3 Polyvalent Interactions and Anti-Infective Polymeric Drugs 95
3.4 Polymeric Drugs for the Treatment of Autoimmune Diseases 105
3.5 Polymeric Anti-Obesity Drugs 107
3.6 Polymer Therapy for Sickle Cell Disease 111
3.7 Conclusions and Outlook on Polymers as Drugs 112
References 113
Chapter 4 Pharmaceutical Applications of Natural Polymers 114
4.1 Introduction 114
4.2 Portals of Drug Administration in the Human Body 116
4.3 Transdermal Drug Delivery Devices 117
4.4 Topical Drug Delivery 124
4.5 Oral Drug Delivery System 131
4.6 Parenteral Drug Delivery Systems 132
4.7 Nasal Drug Delivery Systems 134
4.8 Hydrogel-Based Drug Delivery Systems 136
References 147
Chapter 5 Hydrophobic Polymers of Pharmaceutical Significance 149
5.1 Introduction 149
5.2 Examples of Hydrophobic Polymers and Their Drug Delivery Applications 150
5.3 Conclusions 167
References 168
Chapter 6 Polymers in Drug Delivery 169
6.1 Evolution of Drug Dosage Forms 169
6.2 Polymer Excipients 172
6.3 Polymers as Manufacture Aids and Sustained Release 174
References 200
Chapter 7 Pharmaceutical Nanotechnology: Overcoming Drug Delivery Challenges in Contemporary Medicine 202
7.1 Challenges in Delivery of Contemporary Therapeutics 202
7.2 Nanotechnology Solutions 207
7.3 Illustrative Examples of Nanotechnology Products 211
7.4 Multifunctional Nanotechnology 218
7.5 Regulatory Issues in Nano-pharmaceuticals 225
7.6 Conclusions and Future Outlook 235
References 235
Chapter 8 Thermal Analysis of Pharmaceutical Polymers 237
8.1 Introduction 237
8.2 Theoretical Background of Thermal Analysis 238
8.3 Physical and Chemical Phenomena Commonly Investigated Using Thermal Approaches 244
8.4 Applications of Thermal Analysis for the Characterisation of Pharmaceutical Raw Materials 248
8.5 Applications of Thermal Analysis for the Characterisation of Pharmaceutical Dosage Forms 250
8.6 Conclusion 255
References 255
Chapter 9 Applications of AFM in Pharmaceutical Polymers 256
9.1 Introduction 256
9.2 Use of AFM in Pharmaceutical Sciences 263
9.3 AFM Combined With Optical or Spectroscopic Techniques 271
9.4 Summary 271
References 273
Chapter 10 Rheology in Pharmaceutically Used Polymers 274
10.1 Introduction 274
10.2 Theoretical Background and Fundamental Concepts 275
10.3 Practical Issues of Rheological Measurements 289
10.4 Application of the Technique 292
10.5 Summary 297
References 297
猜您喜欢
