生物电子学最新进展（英文版）

　　美国国家标准与技术研究所（NIST）将生物电子学定义为生物学与电子学的融合领域。这主要包括两部分内容：一是生物系统中电子学现象，包括研究生物分子的电子学特性、信息的传输和储存；二是利用电子学的手段解决生物学问题，包括利用传感器获取和分析生物信息等。近几十年以来，生物电子学有了飞速的发展，其内涵和外延也不断变化。2015年是东南大学生物电子学国家重点实验室成立30周年。本书汇集了该实验室成立以来的主要研究进展，由实验室的现任研究人员和曾经在实验室工作过的人员编写，其内容涵盖材料与界面、生物传感与芯片、生物信息学和生物医学影像等四个方面，主题包括生物分子相互作用、自组装、单细胞分析、生物芯片、生物信息学、神经接口、多模态成像技术等，这些也是生物电子学的重要内容。本书适合生物医学工程、电子工程、分析化学、材料工程和生物工程，以及其他生物医学相关专业的本科生、研究生及研究人员阅读和参考。

　　顾忠泽 编

Preface
Chapter 1 The Photoelectric Detection at the Single Cell Level
1．1 Introduction
1．2 Dielectrophoresis
1．3 Optical Tweezers
1．4 Microfluidics
1．5 Microelectrodes
1．6 Conclusions
References
Chapter 2 Development of Multiple Transmission-Reflection Infrared Spectroscopy
2．1 Introduction of Infrared Absorption Methodologies for Thin Films
2．2 Optical Theory
2．3 Grazing Angle Mirror-Backed Reflection
2．4 Multiple Transmission-Reflection Infrared Spectroscopy
2．5 Orientation Analyses with IR Spectroscopy
2．6 Summary
References
Chapter 3 Molecular Interactions at Model Cell Membranes Investigated Using Nonlinear Optical Spectroscopy
3．1 Introduction
3．2 Sum Frequency Generation Vibrational Spectroscopy
3．3 Interactions Between Model Cell Membranes and Small Drug Molecules
3．4 Interactions Between Model Cell Membranes and Nanomaterials
3．5 Interactions Between Model Cell Membranes and Peptides
3．6 Interactions of Membrane Associated Proteins
3．7 Conclusions and Outlooks
3．8 Acknowledgement
References
Chapter 4 Microparticle Based Biochips' Preliminary Subsections
4．1 Introduction
4．2 Plain Microparticles
4．3 Encoded Microparticles
4．4 Microparticles and Chips
4．5 Instrumentation for Microparticles Analysis
4．6 Conclusions and Prospective
References
Chapter 5 Biomedical Applications of Zwitterionic Antifouling Polymers Based Nanoparticles
5．1 Introduction
5．2 Biomedical Applications of Zwitterionic Nanoparticles
5．3 Conclusions and Outlooks
References
Chapter 6 Nucleosome Organization Around Transcriptional Sites and Its Role in Gene Regulation
6．1 Introduction
6．2 Nucleosome Depletion Upstream of Transcription Start Sites
6．3 Nucleosome Occupancy Around Transcriptional Splice Sites
6．4 Nucleosome Positioning in the Vicinity of Transcription Termination Sites
6．5 Nucleosome Occupancy Patterns Around Transcription Factor Binding Sites
6．6 Conclusions
References
Chapter 7 Virtual and Augmented Reality in Medical and Biomedical Education
Chapter 8 Relating Information in EEGs to Neurocognitive Processes
Chapter 9 Detection， Processing， and Application of Neural Signals
Chapter 10 Cerebral Glioma Grading Using Bayesian Network with Features Extracted from Multi-modal MRI
Chapter 11 Histotripsy： Image-guided， Non-invasive Ultrasound Surgery for Cardiovascular and Cancer Therapy
Color Inset