书籍详情
黄皮酰胺的化学和生物学活性(The Chemistry and Biological Activ)
作者:俞晓明,王琰 副主编,张均田 编
出版社:化学工业出版社
出版时间:2014-07-01
ISBN:9787122206206
定价:¥150.00
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内容简介
《黄皮酰胺的化学和生物学活性(全英文版)》,本书共15章,反映了黄皮酰胺研究的热点和最新进展。本书由我国著名药理学家张俊田教授组织编写,国内相关专家对其所擅长的领域编写,各章具有较高学术水平。本书可供从事相关新药研究的科研人员参考阅读。
作者简介
暂缺《黄皮酰胺的化学和生物学活性(The Chemistry and Biological Activ)》作者简介
目录
Overview: Recent Advances in the Study of (-)Clausenamide on Chemistry,
Biological Activities and Mechanism of Action 1
The Synthesis of Clausenamide Family Natural Products and Analogues 14
Pharmacological Activity of Clausenamide as A Chiral Drug 33
Neuroprotection of (-)Clausenamide via Inhibiting Tau Hyperphosphorylation
and Preserving Microtubule Structure 49
Synaptic Pharmacology of Clausenamide 64
Two Forms of Long-term Potentiation Induced by (-)Clausenamide and Rgl 73
The Nootropic Mechanism of (-)Clausenamide 80
Mechanism of (-)Clausenamide Induced Calcium Transient in Primary Culture
of Rat Cortical Neurons 85
(-)Clausenamide Enhances the Synaptic Plasticity through Gasotransmitters 96
Antiapoptotic Effect of (-)Clausenamide and its Mechanisms of Action 107
The Signal Transduction Pathway of (-)Clausenamide on Activation of
Learning and Memory 114
Pharmacokinetics and Metabolism of Clausenamide Enantiomers 119
Metabolic Transformation of Clausenamide 142
Preclinical Safety Evaluation and General Pharmacology of (-)Clausenamide 148
Optical Separation and Quality Research of Clausenamide Enantiomers 157
Abstracts in English and Chinese 173
Biological Activities and Mechanism of Action 1
The Synthesis of Clausenamide Family Natural Products and Analogues 14
Pharmacological Activity of Clausenamide as A Chiral Drug 33
Neuroprotection of (-)Clausenamide via Inhibiting Tau Hyperphosphorylation
and Preserving Microtubule Structure 49
Synaptic Pharmacology of Clausenamide 64
Two Forms of Long-term Potentiation Induced by (-)Clausenamide and Rgl 73
The Nootropic Mechanism of (-)Clausenamide 80
Mechanism of (-)Clausenamide Induced Calcium Transient in Primary Culture
of Rat Cortical Neurons 85
(-)Clausenamide Enhances the Synaptic Plasticity through Gasotransmitters 96
Antiapoptotic Effect of (-)Clausenamide and its Mechanisms of Action 107
The Signal Transduction Pathway of (-)Clausenamide on Activation of
Learning and Memory 114
Pharmacokinetics and Metabolism of Clausenamide Enantiomers 119
Metabolic Transformation of Clausenamide 142
Preclinical Safety Evaluation and General Pharmacology of (-)Clausenamide 148
Optical Separation and Quality Research of Clausenamide Enantiomers 157
Abstracts in English and Chinese 173
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