生物化学

　　本书由美国著名的化学家和生物学家合著，UniversityofWisconsin，UniversityofCalifornia等几十所大学均以此书作为教材。本书适用于1~2学期的生化双语课程教学，也可供研究生及相关研究人员参考。书中安排有3类系列专栏：“生物化学进展”为学生提供最新的学科进展和技术；“深入研究”介绍了一些历史背景和普遍感兴趣的话题，加深和丰富学生对生物化学的理解；“人体生物化学”讲述各种疾病的生物医学基础，让理论贴近生活。该版本新增“分子马达”一章。本书内容第一部分为细胞的分子构成，包括生物现象的化学基础，水、pH及离子平衡，生物系统的热力学，氨基酸，蛋白质的生物功能及三维结构，糖类，脂质，细胞膜和细胞表面，细胞膜与物质运输，核苷酸和核酸，核酸的结构，重组DNA；第二部分为蛋白质动力学，包括酶促反应动力学，酶的专一性和调节，酶的作用机制，分子马达；第三部分为代谢及其调节，阐述代谢总论，糖酵解作用，三羧酸循环，电子传递和氧化磷酸化作用，光合作用，生糖作用、糖原代谢和戊糖磷酸途径，脂肪酸代谢，脂类的生物合成，氮的获取和氨基酸代谢，核苷酸的合成和降解，代谢整合和途径的单向性；第四部分为信号传递，介绍DNA的复制和修复，DNA的重组和突变，转录和基因表达调控，遗传密码，蛋白质的合成和降解，胞外信号的接收和传递等。

暂缺《生物化学》作者简介

Abbreviations
Preface
Section A-Cells and their structure
A1 Prokaryote cell organization
A2 Eukaryote cell organization
A3 Microscopy
A4 Subcellular fractionation
Section B-Amino acids and proteins
B1 Amino acid structure
B2 Protein structure
B3 Protein structure related to function
B4 Protein purification
B5 Chromatography of proteins
B6 Electrophoresis of proteins
B7 Protein sequencing
Section C-Enzymes
C1 Introduction to enzymes
C2 Factors affecting enzyme activity
C3 Enzyme dinetics and inhibition
C4 Control of enzyme activity
Section D-Antibodies
D1 The immune system:overview
D2 Antibody structure
D3 Polyclonal and monoclonal antibodies
D4 Antibody synthesis
D5 Antibodies as tools
Section E-Membranes:structure and function
E1 Membrane structure
E2 Membrane proteins
E3 Tuansport of small molecules
E4 Transport of macromolecules
E5 Cell signaling
Section F-DNA structure and replication
F1 DNA structure
F2 DNA organization in chromosomes
F3 DNA replication in prodaryotes
F4 DNA replication in eukaryotes
Section G-RNA synthesis and processing
G1 RNA structure
G2 Gene transcription in prokaryotes
G3 Gene transcription in eukaryotes:overview
G4 Expression of eukaryotic protein-coding genes
G5 Expression of eukaryotic rRNA and tRNA genes
G6 Control of gene transcription in prokaryotes
G7 Control of gene transcription in eukaryotes
Section H-Protein synthesis and modification
H1 The genetic code
H2 Protein synthesis(translation)
H3 Protein targeting
H4 Protein glycosylation
Section I-Recombinant DNA technology
I1 Restriction enzymes
I2 Nucleic acid hybridization
I3 DNA cloning
I4 Viruses
I5 DNA sequencing
I6 Polymerase chain reaction(PCR)
Section J-Carbohydrate metabolism
J1 Monosaccharides and disaccharides
J2 Polysaccharides and oligosaccharides
J3 Glycolysis
J4 Gluconeogenesis
J5 Pentose phosphate pathway
J6 Glycogen degradation and synthesis
J7 Control of glycogen metabolism
Section K-Lipid metabolism
K1 Strctures and roles of fatty acids
K2 Fatty acid breakdown
K3 Fatty acid synthesis
K4 Metabolism of triacylglycerols
K5 Cholesterol metabolism
K6 Lipoproteins
Section L-Respiration and energy
L1 The citric acid cycle
L2 Electron transport and oxidative phosphorylation
L3 Photosynthesis
Section M-Nitrogen metabolism
M1 Nitrogen fixation and assimilation
M2 Amino acid metabolism
M3 The urea cycle
M4 Hemes and chlorophylls
Section N-Cell specialization
N1 Muscle contraction
N2 Microtubules,cllia and flagella
N3 Nerve conduction
N4 Collagen
Further reading
Index