生物信息学

　　“精要速览系列（InstantNotesSeries）”是国外教材“BestSeller”榜的上榜教材。该系列结构新颖，视角独特；重点明确，脉络分明；图表简明清晰；英文自然易懂，被国内多所重点院校选用作为双语教材。先锋版是继“现代生物学精要速览”之后推出的跨学科的升级版本。本书是该系列中的《生物信息学》分册，全书共15章，全面系统地概括了该学科的核心内容和前沿动态，涉及生物学数据的获得与处理、系统发生学、芯片数据分析、蛋白质组数据分析、生物信息学的应用等主要内容。本书是指导大学生快速掌握生物信息学基础知识的优秀教材，也是辅助教师授课的极佳教学参考书，同时可供生命科学相关专业的研究生参考。

暂缺《生物信息学》作者简介

Abbreviations
Preface
SectionA-Overviewofbioinformatics
A1Thescoeofbioinformatics
A2BioinformaticsandtheInternet
A3UsefulbioinformaticssitesontheWWW
SectionB-Dataacquisition
B1SequencingDNA,RNAandproteins
B2Determinationofproteinstructure
B3Geneandproteinexpressiondata
B4Proteininteractiondata
SectionC-Databases-contents,structureandannotation
C1Fileformats
C2Annotatedsequencedatabases
C3Genomeandorganism-specificdatabases
C4Miscellaneousdatabases
SectionD-Retrievalofbiologicaldata
D1DataretrievalwithEntrezandDBGET/LinkDB
D2DataretrievalwithSRS(sequenceretrievalsystem)
SectionE-Searchingsequencedatabasesbysequence
E1Sequencesimilaritysearches
E2Aminoacidsubstitutionmatrices
E3Databasessearches:FASTAandBLAST
E4Sequencefilters
E5IterativedatabasesearchesandPSI-BLAST
SectionF-Multiplesequencealignmentandfamilyrelationships
F1Multiplesequencealignmentandfamilyrelationships
F2Proteinfamiliesandpatterndatabases
F3Proteindomainfamilies
SectionG-Phylogenetics
G1Phylogenetics,cladisticsandontology
G2Buildingphylogenetictrees
G3Evolutionofmacromolecularsequences
SectionH-Sequenceannotation
H1Principlesofgenomeannotation
H2Annotationtoolsandresources
SectionI-Structuralbioinformatics
I1Conceptualmodelsofproteinstructure
I2Therelationshipofproteinthree-dimensionalstructuretoproteinfunction
I3Theevolutionofproteinstructureandfunction
I4Obtaining,viewingandanalyzingstructuraldata
I5Structuralalignment
I6Classificationofproteinsofknownthree-dimensionalstructure:CATHandSCOP
I7Introductiontoproteinstructureprediction
I8Structurepredictionbycomparativemodeling
I9Secondarystructureprediction
I10Adnancedproteinstructurepredictionandpredictionstrategies
SectionJ-Microarraydataanalysis
J1Microarraydata:analysismethods
J2Microarraydata:toolsandresources
J3SequencesamplingandSAGE
SectionK-Proteomicdataanalysis
K1Analyzingdatafrom2D-PAGEgels
K2Analyzingproteinmassspectrometrydata
SectionL-Higher-ordersystems
L1Modelingandreconstructingmolecularpathways
L2Proteininteractioninformatics
L3Higher-ordermodels
SectionM-Cheminformaticsinbiology
M1Conventionsforrepresentingmolecularpathways
M2Cheminformaticsresources
SectionN-Bioinformaticsinthepharmaceuticalindustry
N1Bioinformaticsanddrugdiscovery
N2Pharmainformaticsresources
SectionO-Basicprinciplesofcomputinginbioinformatics
O1Runningcomputersoftware
O2Computeroperatingsystems
O3Softwaredownloadingandinstallation
O4Databasemanagement
Furtherreading
Glossary
Index