书籍详情
糖生物学：英文版
作者：（ ）Ajit Varki等著
出版社：清华大学出版社
出版时间：2002-01-01
ISBN：9787302054870
定价：¥49.00
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内容简介
糖生物学是20世纪90年代才发展起来的生物化学中的最后的一个巨大学术前沿领域。糖生物学有着广阔的应用前景——它是生物化学和生物医学学科交叉的新前沿。.国际著名糖生物学家美国加州大学Ajit Varki教授、Jeffrey Esko教授、 Jamey Marth教授以及美国霍普金斯医学院Gerald Hart教授等名校名家共同编写了这本《糖生物学》教材。他们以深厚的专业素养、广阔的学术视野、清晰的思路、优美的文笔，把一个蓬勃发展、精彩纷呈的学术领域呈现在读者面前，引领读者步入糖生物学的科学殿堂！..本书适合高等院校生命学院、医学院及相关专业老师和学生以及从事糖生物学研究的研究人员阅读和参考。...
作者简介
暂缺《糖生物学：英文版》作者简介
目录
Foreword,vii.
Preface,ix
Contributors,xiii
Abbreviatioffs,xv
GENERALPRINCIPLES.
1HistoricalBackgroundandOverview,1
2SaccharideStructureandNomenclature,17
3EvolutionofGlycanDiversity,31
4Protein-GlycanInteractions,41
5ExploringtheBiologicalRolesofGlycans,57
BIOSYNTHESIS,METABOLISM,ANDFUNCTION
6MonosaccharideMetabolism,69
7N-Glycans,85
8O-Glycans,101
9Glycosphingolipids,115
10GlycophospholipidAnchors,131
11ProteoglycansandGlycosaminoglycans,145
12OtherClassesofGolgi-derivedGlycans,161
13NuclearandCytoplasmicGlycosylation,171
14TheO-GIcNAcModification,183
15SialicAcids,195
16StructuresCommontoDifferentTypesofGlycans,211
17Glycosyltransferases,253
18DegradationandTurnoverofGlycans,267
19Glycosylationin"Model"Organisms,285.
20GlycobiologyofPlantCells,305
21BacterialPolysaccharides,321
PROTEINSTHATRECOGNIZEGLYCANS
22DiscoveryandClassificationofAnimalLectins,333
23P-typeLectins,345
24I-typeLectins,363
25C-typeLectins,379
26Selectins,391
27S-typeLectins(Galectins),417
28MicrobialGlycan-bindingProteins,429
29Glycosaminoglycan-bindingProteins,441
30PlantLectins,455
GLYCANSINGENETICDISORDERSANDDISEASE
31GeneticDisordersofGlycosylationinCulturedCells,469
32NaturallyOccurringGeneticDisordersofGlycosylation,479
33DeterminingGlycanFunctionUsingGeneticallyModifiedMice,499
34GlycosylationChangesinOntogenyandCellActivation,515
35GlycosylationChangesinCancer,537
36GlycobiologyofProtozoalandHelminthicParasites,551
37AcquiredGlycosylationChangesinHumanDisease,565
METHODSANDAPPLICATIONS
38StructuralAnalysisandSequencingofGlycans,581
39ChemicalandEnzymaticSynthesisofGlycans,599
40NaturalandSyntheticInhibitorsofGlycosylation,609
41GlycobiologyinBiotcdmologyandMedicine,625
Glossary:CommonlyUsedTerms,635
Index,641...
Preface,ix
Contributors,xiii
Abbreviatioffs,xv
GENERALPRINCIPLES.
1HistoricalBackgroundandOverview,1
2SaccharideStructureandNomenclature,17
3EvolutionofGlycanDiversity,31
4Protein-GlycanInteractions,41
5ExploringtheBiologicalRolesofGlycans,57
BIOSYNTHESIS,METABOLISM,ANDFUNCTION
6MonosaccharideMetabolism,69
7N-Glycans,85
8O-Glycans,101
9Glycosphingolipids,115
10GlycophospholipidAnchors,131
11ProteoglycansandGlycosaminoglycans,145
12OtherClassesofGolgi-derivedGlycans,161
13NuclearandCytoplasmicGlycosylation,171
14TheO-GIcNAcModification,183
15SialicAcids,195
16StructuresCommontoDifferentTypesofGlycans,211
17Glycosyltransferases,253
18DegradationandTurnoverofGlycans,267
19Glycosylationin"Model"Organisms,285.
20GlycobiologyofPlantCells,305
21BacterialPolysaccharides,321
PROTEINSTHATRECOGNIZEGLYCANS
22DiscoveryandClassificationofAnimalLectins,333
23P-typeLectins,345
24I-typeLectins,363
25C-typeLectins,379
26Selectins,391
27S-typeLectins(Galectins),417
28MicrobialGlycan-bindingProteins,429
29Glycosaminoglycan-bindingProteins,441
30PlantLectins,455
GLYCANSINGENETICDISORDERSANDDISEASE
31GeneticDisordersofGlycosylationinCulturedCells,469
32NaturallyOccurringGeneticDisordersofGlycosylation,479
33DeterminingGlycanFunctionUsingGeneticallyModifiedMice,499
34GlycosylationChangesinOntogenyandCellActivation,515
35GlycosylationChangesinCancer,537
36GlycobiologyofProtozoalandHelminthicParasites,551
37AcquiredGlycosylationChangesinHumanDisease,565
METHODSANDAPPLICATIONS
38StructuralAnalysisandSequencingofGlycans,581
39ChemicalandEnzymaticSynthesisofGlycans,599
40NaturalandSyntheticInhibitorsofGlycosylation,609
41GlycobiologyinBiotcdmologyandMedicine,625
Glossary:CommonlyUsedTerms,635
Index,641...
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